HELICOBACTER PYLORI IN HEALTH AND DISEASE: ITS CONTRIBUTION TO GASTROINTESTINAL DISORDERS AND SYSTEMIC METABOLIC EFFECTS

Helicobacter pylori in Health and Disease: Its Contribution to Gastrointestinal Disorders and Systemic Metabolic Effects

Helicobacter pylori is one of the most common human infections worldwide and it is estimated that more than half of global population is affected.This microorganism induces HIGH SHINE oxidative stress in gastric mucosa and causes chronic gastritis, duodenal peptic ulcer, gastric cancer, and as reasonably suspected a number of extragastric diseases

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Calculating and comparing codon usage values in rare disease genes highlights codon clustering with disease-and tissue- specific hierarchy.

We designed a novel strategy to define codon usage bias (CUB) in 6 specific small cohorts of human genes.We calculated codon usage (CU) values in 29 non-disease-causing (NDC) and 31 disease-causing (DC) human genes which are highly expressed in 3 distinct tissues, kidney, muscle, Face Serum and skin.We applied our strategy to the same selected gene

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